Eric Lefkofsky is an American businessman, the self-made billionaire co-founder of Groupon (NASDAQ: GRPN) and the founder and CEO of Tempus, a leading provider of technology-enabled precision medicine solutions. Born in 1969, his career is defined by serial entrepreneurship, high-stakes venture capital, and a profound pivot from e-commerce to medical technology.

He graduated from the University of Michigan and secured a Juris Doctor (J.D.) degree from the University of Michigan Law School. His early career focused on investment, venture capital, and identifying structural inefficiencies in traditional industries. His shift to healthcare technology was inspired by a personal mission: his wife was diagnosed with breast cancer, leading him to recognize the immense fragmentation and inefficiency in medical data—the genesis of Tempus.

Eric Lefkofsky's entrepreneurial journey includes founding five technology companies. He co-founded and led a series of successful ventures: Echo Global Logistics (2005) (logistics outsourcing), InnerWorkings (2001) (marketing execution), and Mediaocean (media procurement technology). He is most famous for co-founding and serving as Chairman of Groupon (2008), the global e-commerce marketplace, which executed a massive IPO in 2011.

His pivot to healthcare began with the founding of Tempus in 2015. Tempus is built on the ambitious vision of using AI and machine learning to collect, analyze, and apply massive amounts of clinical and molecular data to personalize cancer treatment (precision medicine). Tempus achieved a multi-billion dollar valuation and successfully executed a Series G-2 in late 2020 (valuing the company at $8.1 billion), expanding its focus to mental health, cardiology, and diabetes. Lefkofsky is also a founding partner of the venture fund Lightbank, securing his multi-billion dollar fortune.

Eric Lefkofsky's philanthropy is structural and mission-driven, focusing on advancing high-impact initiatives in education, science, and the arts through the Lefkofsky Family Foundation. His structural social impact is tied to Tempus's mission to transform cancer treatment by leveraging AI and molecular data, providing a potentially world-changing contribution to precision medicine.

He is an adjunct professor at the University of Chicago and serves as a Trustee for major Chicago institutions (Lurie Children's Hospital, Steppenwolf Theatre Company), reflecting his commitment to his adopted city's cultural and scientific vitality.

Eric Lefkofsky maintains the professional, intellectual style of a serial tech founder. His attire is consistently formal and high-quality, favoring tailored suits. His aesthetic is one of serious, data-driven authority, reflecting his background in law and economics and his commitment to applying AI to medicine.

Residing in Chicago, his luxury is the immense security and autonomy derived from his multi-billion dollar fortune. His life is defined by his commitment to technology, entrepreneurship, and his profound, mission-driven pivot to solving the structural problems of healthcare through artificial intelligence.