O ran Holtzman is the co-founder and CEO of Oddity Tech, a beauty and wellness company that leverages artificial intelligence to develop and market products. He founded the company in 2018 with his sister, Shiran Holtzman-Erel, aiming to disrupt the traditional beauty industry with a data-driven approach. Oddity is the parent company of popular brands Il Makiage and SpoiledChild, which utilize proprietary algorithms to match consumers with the perfect makeup and skincare products online, bypassing physical retail stores.

Holtzman's vision of "beauty tech" has proved highly lucrative, with the company achieving rapid growth and profitability. He successfully led Oddity to a public listing on the Nasdaq in July 2023, valuing the company at nearly $2.7 billion. Under his leadership, Oddity has acquired biotechnology startups to further enhance its product development capabilities. Holtzman's stake in the company has made him a billionaire, representing a new wave of entrepreneurs merging consumer goods with advanced technology.